Vaccine Definition- Type of Vaccine,History of Vaccine

Vaccine Definition– Vaccine is an ingredient or substance that helps to protect against particular diseases. The vaccine contains an ingredient that similar to the pathogenic organism and it made from a weak or deadly form of germ, its toxin or protein on its surface. This substance detects the living microbes and destroy it and protect your immune system for future infection.

Vaccine Definition and Types of Vaccine

Vaccine Definition

There are different types of vaccines. Each and every type of Vaccine are design to instruct you. How to fight a certain type of germ and the diseases they cause.

Base on some factors. They look the immune system responds to the germ, who actually need to be vaccinated against germ and the best method for vaccine production.

ReadBoostrix vaccine

Scientists make the 4 types of vaccines like

1〉 Live attenuated Vaccines

2〉 Inactive Vaccines

3〉 Subunit, recombinant, Polysaccharide, and conjugate Vaccines

4〉 Toxoid Vaccine

Live Attenuated Vaccines

Live attenuated vaccines

Live attenuated vaccines use a weakened form germ that causes disease. These vaccines are very similar to the natural infections that they help to prevent. Live Vaccines create a long-lasting Immune response.  Most of the live vaccine can give you lifetime protection against germ and diseases it causes.

Looks like live vaccine are very beneficial Know? But they have their limitations.

These Vaccines always need to be stored in a cool place. Which means they can not be used in countries with limited access to the fridge.

Live vaccines not for all because they contain a small amount of attenuated virus. Before accepting them you should take advice from the health care providers. If any person has a long term health problem, a weak immune system and any kind of organ transplant. They should not take live Vaccines.

Live Vaccines are normally used to protect against


Vaccine Definition
Credit- Mediline plus


Yellow Fever


Rubella, Mumps, Measles

Inactive Vaccine Definition

This Vaccine is an alternative to Live vaccines but does not provide protection like live vaccines. This type of inactive Vaccines are created by formaldehyde or formin (inactivating a pathogen). You need some doses overtime to get the immunity going against the diseases.

This Vaccine is protecting against 


Polio vaccine
Credit- BBC


Hepatitis A


Subunit Vaccine Definition, Conjugate vaccine, Recombinant Vaccines

This type of Vaccine almost used everyone who really needs it. People like long term health problems and weak immune systems. These vaccines provide a very strong immune response target to the root of germ.

This vaccine is used to protect against

Hepatitis B



Whooping cough and Shingles

ReadRotateq Vaccine

Polysaccharide vaccines

Polysaccharide vaccine

For making this vaccine polysaccharide molecule taken from encapsulating bacteria like  23 streptococcus pneumoniae.

Recombinant Vaccine Definition

These vaccines are made from yeast cells. Yeast cell is used for the human papillomavirus schedule vaccine infantry Hexa, Gardasil 9 respectively.

Conjugate Vaccines

Initial days researchers notice that polysaccharide Vaccines do not work well for infants and young children. The scientist discovers something new that if the Polysaccharide linked to something else than, It creates a stronger immune system (Like tetanus toxoid protein or Diptheria). The immune system recognizes this protein very easily and it helps to create a stronger resistance to Polysaccharide.

Toxoid Vaccines Definition

Toxoid Vaccine

Some kind of bacteria release protein, when they attack the body. But our immune system recognizes this protein same way it recognizes the polysaccharide on the surface of the bacteria. Some vaccines are created with inactivated versions of these toxins. This kind of vaccine calls a Toxoid vaccine.

This vaccine is used UK schedule process

Diphtheria Vaccine

Tetanus Vaccine

Pertussis Vaccine

Researchers are still working o developing new vaccines, The two examples are

DNA Vaccine Definition– These vaccines are still available for veterinary use but not available for humans. But scientists work to develop a vaccine for humans as well as several cancers.

Recombinant Vector Vaccines – These types of vaccines are especially created to teach the immune system, how to fight with a germ.

History of Vaccination

In 1796 the first Vaccines are invented by Edward Jenner for protection against smallpox. This procedure was an experiment by taking material from a blister of an infected person with cowpox and inoculating it on the other person’s skin. This procedure was called arm to arm inoculation.

However, by the end of the 1980s, scientists’ knowledge had been developed enough to allow large scale vaccine production and control the disease could be initiated.

Smallpox, Diphtheria, Tetanus, and pertussis are the late 1940s recommended vaccines.

Polio Vaccines are the most awaited vaccines

Vaccine Definition

Every summer parents are so scared because of the polio epidemic. They try to keep their children away from the swimming pool. Send them to stay with relatives in their country. Pray for understanding about the spread of polio. In 1955 the polio vaccine was licensed by the Jonas Salk. He becomes the overnight hero.

Smallpox, Diphtheria, Tetanus, Pertussis, and Polio are the 1950 invented Vaccines.

Mumps, Measles, and rubella vaccines are invented in 1960

1967 measles vaccines are available to protect against mumps. Rubella vaccines are available in 1969 and the combination of these three vaccines is available called MMR vaccine in 1971.

Smallpox, Diphtheria, Tetanus, Pertussis, Polio, Measles, Mumps and Rubella vaccines are available at the end of 1960.

Diphtheria, Tetanus, Pertussis, Polio, Measles, Rubella and Mumps are recommended vaccines in 1970.

From 1985 to 1989 the Hepatitis B vaccine was invented and schedule. In 1989 the vaccine schedule is published again.

This Hepatitis B vaccine is mostely recommended to those infants. whose mother was Hepatitis B positive, Homosexual men, Intravenous drug users and people with multiple sex partners? Hepatitis B disease was virtually eliminated in the united state under the age of 18.

HIB, Hepatitis B, Polio, Rubella, Mumps, Measles, Pertussis, Tetanus and Diphtheria Vaccine are the most recommended vaccines from 1994 to 1995.

Some Schedule updated vaccine from 1995 to 2010

Chickenpox vaccine varicella updated in 1996. Rotavirus updated in 1998, 1999, 2006 and 2008. Hepatitis A update in 2000 and in  2001 pneumococcal vaccine updated.

In 2000 the Discontinuation of the vaccine was updated to the oral polio vaccine.

Some 2005 and 2010 recommend vaccine are

Year 2005Year 2010   
Hepatitis BHepatitis B
Hepatitis AHepatitis A
InfluenzaInfluenza and Rotavirus

Updated Vaccines from 2011 to 2019

In 2014 meningococcal serogroup B vaccine schedule was updated.

In the 2011 HPV vaccine schedule and 2018, the intranasal influenza vaccine was updated.

2019 Recommended Vaccine Definition

Diphtheria, Tetanus, Pertussis, Measles, Mumps, Rubella, Polio, Hib, Hepatitis B, Varicella, Hepatitis A, Pneumococcal, Influenza, Rotavirus.

Question and Answers About Vaccine Definition

Credit– CDC

1〉 What vaccine are most important?

Diphtheria, Tetanus and Pertussis Vaccines.

PCV (Pneumococcal Conjugate vaccine)

IPV (Inactivated poliovirus Vaccine)

All hepatitis B vaccination.

2〉 What are the risks of Vaccines?

some minor side effects like Fussiness, Grade Fever, Fatigue, Temporary Headache.

3〉 What are the risks of not Vaccinating?

Without vaccinating there is a chance of always suffering from pain, Disability, Serious ill and diseases like whooping cough and measles.


In this article, we try to cover everything about Vaccine Definition, Type of Vaccine and History of Vaccine. We hope you like this article.


ReadAFM Vaccine

ReadPPSV23 Vaccine