Pentavalent Vaccine is a very helpful vaccine. Because this one vaccine is a solution of 5 diseases like Diphtheria, Pertussis, Tetanus, Hepatitis B and HIB. This one vaccine contains 5 antigens.
The vaccine also is known as a 5 in 1 vaccine. This pentavalent vaccine is widely available in many pediatric combination vaccines, especially in middle and low-income countries.
In 2013 Pentavalent Vaccines were 100% of the DTP-rich vaccines procured by UNICEF.which supplies vaccines to a large portion of children worldwide.
- 1 Advantage Of Pentavalent Vaccine
- 2 The perfect age Pentavalent Vaccine administered
- 3 The history of this Vaccine
- 4 Formulations of Pentavalent Vaccine
- 5 Side Effects of Pentavalent Vaccine
- 6 The Ingredients of this vaccine
- 7 Vaccine Route of Administration
- 8 Schedule of this vaccine under UIP
- 9 The pentavalent vaccine protects against 5 Diseases
- 10 Storage
- 11 Some questions and answers about the Pentavalent Vaccine
Advantage Of Pentavalent Vaccine
Arrangement for the addition of the HIB vaccine another protection against the deadly disease. The number of injections administered under UIP during the first year of life reduces from nine to six. The pentavalent vaccine does not require any reconstitution.
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The perfect age Pentavalent Vaccine administered
According to the National Immunization Schedule. The vaccine should be started for any child more than 6 weeks of age and given up to 1 year of age.
The history of this Vaccine
The European Medicines Agency granted Pentavantent in October 2004.
The first Pentavalent Vaccine formulation receives pre-qualification approval from the World health organization in 2006.
Pentavalent were 100% of the DTP- containing vaccine procured by UNICEF in 2013. Which provides vaccines to a large part of the world children.
South Sudan Become the last of the GAVI supported countries to launch a five in one vaccine.
UNICEF announced a US$110 million awards to supply its Pentavalent pediatric vaccine Quinvaxem to the developing world.
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Formulations of Pentavalent Vaccine
The normal version of the pentavalent vaccine includes Pentavac PFS, ComBE Five, Shan5, Pentabio and Quinvaxem.
|Vaccine||Manufacturer||Date pre Qualified By WHO|
|Pentavac PFS||Serum Institute of India||23 June 2010|
|ComBE Five||Biological E. Limited||1 September 2011|
|EasyFive TT||Panacea Biotec||2 October 2013|
|Shan5||Shantha Biotechnics||29 April 2014|
|Pentabio||Bio Farma||19 December 2014|
|Quinvaxem||Crucell||26 September 2006|
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Side Effects of Pentavalent Vaccine
Very common side effect after any vaccination is
Loss od appetite
Redness appears at the injection site.
The mentioned side effects can be relieved by giving Paracetamol. If your child more then 2 months give Calpol or Ibuprofen if your child more than 3 months of age and weight should be more than 5 Kg.
Some rare side effects are
Fits high temperatures sometimes.
Abnormal high pitched screaming and Hypotonic Hypersponsive episodes. The child may become pale, Blue and Limp.
After vaccination, if you notice any of these symptoms, you must consult with your doctor.
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The Ingredients of this vaccine
In vaccine united kingdom use a very small amount of active ingredients like
Polysorbate (it is normally used as an emulsifier to hold the ingredients together)
Lactose and Medium 199(it contains mineral salt, vitamins, and amino acid).Both ingredients use as a stabilizer.
A small amount of Phenol used as a preservative.
A small amount of aluminum, which strengthens and lengthens the immune response to the vaccine.
HIB is a part of the vaccine. Sugar is taken from capsules around the HIB and added to non-toxic protein from Tetanus. Protein helps to awaken immunity in a broad way by responding well to the vaccine. It responds to better resistance in individuals of all ages.
The polio component of the vaccine is born in the laboratory using a strain of animal cells.
In the UK these ingredients are used but other countries may use other ingredients.
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Vaccine Route of Administration
Anterolateral aspect of mid-thigh LEFT
Site of Injection
Schedule of this vaccine under UIP
According to the National Immunization Schedule, three doses of pentavalent vaccine are to be administered at 6,10 and 14 weeks of age.
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The pentavalent vaccine protects against 5 Diseases
Like other vaccines, this vaccine also stores in a 2 to 8-degree Celcius in the refrigerator. It should not be stored in a Frozen section.
Is Booster Dose is recommended under UIP?
A booster dose is not recommended for the pentavalent vaccine under UIP.
Some questions and answers about the Pentavalent Vaccine
How do you Give Pentavalent Vaccine?
This vaccine must be given intramuscularly into the opposite thigh. First, clean the thigh area with an antiseptic solution then dry it. After dry inject 0.5 mL of vaccine. Because the HIB vaccine provides protection for at least 15 years.
Is Pentavalent Vaccine Is Safe?
Yes, the pentavalent vaccine is very safe. According to the test and study, it was found that the DTPw-HepB-Hib vaccine was very safe.
What is DTap DTP TD?
This is a combined vaccine against Diptheria, Tetanus, and Pertussis. The pertussis component is acellular.
What age can this vaccine be administered?
This vaccine can be given to any child age for more than 6 weeks and up to 1 year of age.
There is any reason a child should bot be given this Vaccine?
If a child previously faces a problem with the pentavalent vaccine.
Why the Hib vaccine is given as a Pentavalent Vaccine and not given separately?
The vaccination schedule for Hep B, DPT and Hib is the same time at 6,10 and 14 weeks. Therefore if these three vaccines are given individually, a child receives three pricks at the same time. The pentavalent vaccine reduces the number of pricks.
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