Pentacel Vaccine Dose, Side Effects, Interection,Price

Pentacel Vaccine

Pentacel Vaccine is kind of all in one vaccine. Because this vaccine helps to protect against Haemophilus influenza type b, Polio, Tetanus, Diptheria, Pertussis all serious kind of disease by improving your body immunity to this disease.

Polio can affect the central nervous system and spinal cord. This disease can also cause paralysis and muscle weakness. Polio is life-threatening because it can cripple your muscles which helps you to breathe.

Haemophilus B bacteria can affect your brain, lungs, spinal cord, bone, Joint, Blood. It can cause the respiratory problem and these infections can be fatal.

Diphtheria is a highly contagious bacterial infection in the nose and throat. But immunization of the diphtheria disease of the past in most regions of the world. If anyone is not vaccinated from the disease, then it may cause Heart failure, nerve problems, and even death also.

Pertussis is a very dangerous respiratory disease. It can cause by the bacterium Bordetella Pertussis. In this disease, you have to face difficulty in breathing. All ages people can be affected by this disease and extremely serious for under one year of age children.

Tetanus can affect your nervous system and it can lead to pain in Neck Muscle and Jaw Muscle. Swallowing difficulty, Painfull Body spasm, and stiffness of your neck muscle are the common symptoms of this disease.

Those children age between 6 weeks to 4 years old Pentacel Vaccine is very helpful for them to prevent all kinds of mention diseases.

The  Pentacel vaccine Dosage

Pentacel Vaccine

This vaccine should be administered in 4 dosage series like 2, 4,6 and 15 to 18 months of age. The first dose may be given as early as 6 weeks of age.

Pentacel Vaccine 4 dose help to prevent Pertussis. 3 doses of this vaccine help to prevent H influenza type B, Tetanus, diphtheria, and Poliomyelitis.

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Pentacel and Diphtheria vaccine Mixed sequences

Before talking about the Mixed sequence of these vaccines. You should know that no clear safety and efficacy data available in a mixed sequence of the Pentacel vaccine and the DTap vaccine.

Both Pentacel and Dtap vaccines contain the same pertussis antigen which is manufactured by the same process. But the amount of Detoxified pertussis toxin available in twice amount in Pentacel vaccine and four-time amount of FHA as DAPTACEL.

Those children already receive the 4 dosages of the Pentacel vaccine, they should receive the Dtap vaccine using DAPTACEL at  4 to 6 years of age.

Pentacel Vaccine and Haemophilus B Conjugate vaccine mixed sequence

To complete the vaccination series in children and infant Pentacel vaccine may be used with one or more dosage of the Haemophilus B conjugate vaccine. Actually the accurate safety and efficacy data are not available about Pentacel Vaccine in Infant and Children. To complete the vaccination series if other brands are used like Haemophilus B conjugate vaccine, then three primary doses are required to complete the series.

Pentacel Vaccine and IPV Vaccine mixed sequence

Pentacel Vaccine can be used in infants and children who have taken 1 or more dosage of another licensed IPV vaccine. Accurate safety and efficacy data are not available about the Pentacel Vaccine.

According to the advisor, the pentacle vaccine administration time is 2,4,6 and 15 to 18 months. A booster dose of the IPV vaccine should be administered between 4 to 6 years of age.

0.5mL Pentacel vaccine must be given intramuscularly and should be used immediately after reconstitution.

Those children age is less than 1 year of age thigh muscle is the preferred site of injection. For adult and older people deltoid muscle is enough for injection.

The vaccine should not be used in the Gluteal area where the nerve trunk may be present.

Do not mix the Pentacel Vaccine syringe with other syringes or products.

Remember one thing, Before receives any kind of vaccine you should consult with your healthcare provider.

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Pentacel Vaccine Drug Interaction

Most frequently drug interactions are

Daptacel(DTaP)(Diphtheria and tetanus toxoids/pertussis,acellular).

Havrix Pediatric(Hepatitis a pediatric vaccine)

Hiberix(Haemophilus b conjugate (prp-t)vaccine)

Kinrix(diphtheria toxoid/pertussis,acellular/poliovirus vaccine,inactivated/tetanus toxoid)

Pediarix(Diphtheria toxoid/Hepatitis b pediatric vaccine/pertussis,acellular/poliovirus vaccine,inactivated/tetanus toxoid)

Rotarix(Rotavirus Vaccine)

Twinrix(Hepatitis a adult vaccine/hepatitis b adults vaccine)

Rotateq(rotavirus vaccine)

Varivax(Varicella Virus Vaccine)

ProQuad (measles virus vaccine/mumps virus vaccine/rubella virus vaccine/ varicella virus vaccine)

Prevnar(Pneumococcal 7- valent Vaccine)

M-M-R ll(Measles virus vaccine/Mumps virus vaccine/rubella virus vaccine).

Recombivax HB(Hepatitis B pediatric vaccine)

Vaqta Pediatric(Hepatitis a pediatric vaccine)

The price and coupons of the Pentacel Vaccine

The pentacle is a vaccine combination. It is commonly used for Haemophilus influenza prophylaxis, Pertussis Prophylaxis, and Diphtheria Prophylaxis.

In U.S pharmacy the price of Pentacel is around $527 for 5 kits. It is also depending on the pharmacy you visit.

Pentacel Vaccine Side Effects

Pentacel Vaccine

You must consult with your doctor if any of the following side effects occur after receive Acellular/poliovirus vaccine, inactive/tetanus vaccine, diphtheria toxoid/Haemophilus B conjugate vaccine.

Some very common side effects are


Dry Mouth


Loss of Appetite


Chest Pain

Stomach Pain

Shortness of breath


Sore Throat

Wrinkled Skin

Sunken Eyes

Rapid Breathing

Noisy Breathing

Less Common Side effects are

Redness in skin

Slow Breathing


Stiff Neck or back





Fast heartbeat

Severe headache

Joint pain, swelling


General feeling illness

Stuffy Nose

Face, Lips, hand swelling

Severe headache

Flu-like symptoms

Heartbeat fast


Above all side effects. Some side effects are there they do not need any medical attention. But if you have any related questions about your side effects you must ask your health care provider.

Tenderness at the injection site.


Weakness or tiredness

Uncommon side effects

Paleness in skin


Injection site skin color change

Itching, Infection, Coldness, Discoloration, Bleeding, Soreness, Ulceration, Scarring.

Vomiting like feeling

Healthcare Professional

Gastrointestinal side effects include Dehydration, Diarrhea, Appetite decrease, and Gastroenteritis.

General Side effects include

Screaming, Fussiness, Fever, Lethargy, Inconsolable crying.

Hypersensitivity side effects include

Urticaria and Rash

Nervous System side effects include

Meningitis, Seizures, Encephalopathy and Somnolence

Gastrointestinal side effects are

Dehydration, Decreased Appetite, Diarrhea, Gastroenteritis

Cardiovascular side effects include

Pallor and Cyanosis

The history of Vaccine approval

On 20 June 2008, this vaccine first approved by the FDA

The brand name of this vaccine is Pentacel

Diphtheria and Tetanus Toxoids, Inactivated Poliovirus and Haemophilus B Conjugate vaccine are the Generic Name.

Pentacel is a vaccine combination. This helps to protect against Pertussis, Diphtheria, Tetanus, Poliomyelitis.

Before Receive this Pentacel vaccine Must Follow Thigh

Like another vaccine, you consult with the doctor before receiving this vaccine

If you have any allergies reaction to the Pertussis, Diphtheria, Haemophilus. you are not eligible to receive this vaccine.

Your child may not be able to receive Pentacel if he or she has ever had the same vaccine that causes any of the following.

After 6 weeks of vaccination if you have Guillain Barre Syndrome.

Allergies reaction to Polymyxin B, Neomycin and Streptomycin or yeast.

If you have a high fever of more than 104 degrees.

You or your children need to postpone the vaccine schedule. If you have a history of premature birth or seizures.

If your immune system is very poor.

Is Pentacel Vaccine is Safe?

Yes. According to the clinical studies of the combination, the vaccine suggests that it is very safe.

Is Pentacel Preservative Free?

Yes. This vaccine is a preservative-free injection single-dose vial 0.5mL.


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Pentacel Vaccine Dose, Side Effects, Interection,Price
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